Thinking about enhancing your natural beauty or addressing those stubborn skin concerns? You’ve landed in the right place!
Finding the best aesthetic clinic in Indianapolis requires looking for expertise, personalized care, and a philosophy that truly aligns with your specific goals.
Instead of framing it as a simple transactional process, consider it a collaborative journey toward achieving the look you desire.
This list is your comprehensive guide for those subtly seeking to manage the signs of aging, those actively working to tackle issues like pigmentation and acne, or even those who are finally ready to explore popular non-surgical treatments such as injectables.
I’ve carefully rounded up the top spots in Indy that focus on helping you achieve that confident, rejuvenated feeling.
Moreover, these selected clinics prioritize ensuring your results look completely natural, showcasing the very best version of you rather than an altered appearance. By taking a deeper look at the core values and services of these providers, you can make an informed decision that will ultimately lead to satisfying, long-lasting results.
How much does aesthetic treatment cost in Indianapolis?
The cost of cosmetic enhancement in Indianapolis, just like anywhere, depends on what you are having done. If you are considering a neuromodulator to smooth those forehead lines, a procedure like Botox will typically pay per unit, which generally falls between $11 and $14.
For adding volume with dermal fillers, a single syringe often ranges from $500 up to over $900. Remember that surgical procedures are on an entirely different scale and will be significantly higher.
It’s always best to have a consultation so your chosen clinic can provide a clear, customized quote based on your specific treatment plan and needs.
1. Ageless Aesthetics

Website: https://agelessindy.com/
Address: 8860 Zionsville Rd #300c
Contact: +1 317-855-9100
Hours:
- Mon: 10:00 AM – 5:00 PM
- Tue – Wed & Fri: 9:00 AM – 5:00 PM
- Thu: 9:00 AM – 7:00 PM
Ageless Aesthetics is best known for its signature Holy Trifecta approach, a strategic combination of collagen-stimulating treatments, premium injectables, and medical-grade skincare designed to deliver comprehensive, long-lasting results.
Rather than focusing on single injections or quick fixes, the clinic emphasizes a thoughtful, multi-pronged plan that supports skin health over time.
Each treatment plan is built to enhance natural beauty while maintaining balance, subtlety, and consistency.
The goal is undetectable, timeless rejuvenation that never looks overdone, reflecting the clinic’s belief in refinement over drastic change.
To support ongoing care, Ageless Aesthetics offers its forever flawless membership, providing loyal clients with cost savings and structured maintenance for sustained results.
One minor drawback I can see here is the requirement to download a dedicated patient app to access full booking features and exclusive savings, adding an extra step to the otherwise streamlined experience for modern aesthetic clients.
Customer Reviews
Explained the process openly and honestly
Hailey’s bedside manner was amazing! She explained the process openly and honestly and made me as comfortable as possible. She was sure to let me know how to best communicate with her if there were any issues or questions following my appointment. I will definitely be back!
- Erin Tennessen | Google Review
Listens to your needs and slays them!
I highly recommend Ashley Grant. She listens to your needs and slays them! Thank you for helping me feel and look amazing, for my 50th birthday!
- Sara Nielander | Google Review
2. MY Health Care & Aesthetics

Website: https://www.yang-wellness.com/
Address: 941 E 86th St
Contact: +1 317-492-9838
Hours:
- Mon – Fri: 9:00 AM – 5:00 PM
- Sat: 9:00 AM – 12:00 PM
MY Health Care & Aesthetics stands out for its Integrated holistic wellness model, which aligns aesthetic treatments with overall health for a balanced, full-body approach.
This philosophy is ideal for those who believe true beauty and confidence start from within.
By blending traditional medical expertise with advanced aesthetic solutions, the clinic delivers care that is both results-driven and medically grounded.
Every patient begins with a personalized, one-on-one consultation with Dr. Hongmei Yang, a board-certified internist, ensuring treatments are safe, thoughtful, and tailored to individual needs and budgets.
Dr. Yang’s background in immunology further enhances her ability to address complex skin concerns such as acne and pigmentation with a targeted, clinical approach.
Patients can feel confident knowing their aesthetic goals are supported by strong medical oversight.
One consideration is that healthcare services are limited to patients 18 and older, which may not suit families seeking comprehensive care for all ages.
Customer Reviews
Wonderful experience
We had a wonderful experience working with Dr. Yang for our immigration medical exam. She was very approachable, explained things in easy steps. Also it was cost effective compared to other places in Carmel area.
- Mahbubur Rahman | Google Review
Happy with my results
Very happy with my results for sublative laser resurfacing for acne scars. My forehead and temple scars were bad, but she made them dissapear. Dr. Yang is very professional and expert in this particular area for skincare. I highly recommend her to anyone!
- Joseph Miles | Google Review
3. Regeneration Aesthetics

Website: https://www.regenerationaesthetics.com/
Address: 9152 Kent Ave Suite C
Contact: [email protected]
Hours: Mon – Fri: 10:00 AM – 5:00 PM
Regeneration aesthetics stands out for its exclusive focus on non-surgical rejuvenation, delivering noninvasive facial treatments through a highly trained, credentialed team.
The clinic specializes in minimally invasive procedures such as injectables and microneedling, allowing providers to develop deep expertise in these techniques.
Led by board-certified professionals Dr. Linda Burns and Mckenzie Burns, PA-C, the practice offers advanced training, precision, and medical oversight in every treatment.
Their patient-first philosophy emphasizes comfort, privacy, and safety, ensuring clients feel heard and supported throughout their experience.
The clinic is also known for achieving natural-looking results that enhance features without appearing overdone. This makes it an excellent choice for patients seeking subtle, refined improvements rather than dramatic changes.
One consideration is location, as the clinic is based in Indianapolis, which may be less convenient for those living on the far edges of the metro area.
Customer Reviews
Their approach was never “pushy” and my results are amazing!
I could not be pleased anymore with my results from Regeneration Aesthetics! From the moment I walked into the clinic, I felt welcomed and treated so kindly and professionally. They explained my options in great detail after listening to what I wished to achieve. Their approach was never “pushy” and my results are amazing! Their knowledge was so impressive! I highly recommend RA! I definitely will be a repeat customer!
- Laura Crenshaw | Google Review
Made me feel so comfortable as a toxin newbie
This team is professional and welcoming and made me feel so comfortable as a toxin newbie. All my questions were answered, they developed a conservative plan which is what I wanted and even followed up with me at two different intervals following my treatment to see how my results were settling. I highly recommend them!
- Jentry O’Daniel | Google Review
4. Lyfe Aesthetics & MedSpa

Website: https://mylyfemedspa.com/
Address: 3965 N Meridian St Suite C
Contact: +1 317-600-3217
Hours:
- Tue & Fri: 9:00 AM – 7:00 PM
- Wed-Thu & Sat: 9:00 AM – 5:00 PM
Lyfe MedSpa is a great choice if you’re looking for a practice that thoughtfully connects how you look with how you feel.
Their core philosophy, “Where Beauty Meets Wellness,” shines through in their extensive menu, offering a genuinely integrated approach to client care.
This commitment is evident in their offerings, which include standard aesthetic services like dermal fillers and lasers, but also specialized wellness treatments such as a dedicated medical weight loss program.
Additionally, they utilize advanced techniques like Plasma-rich Fibrin (PRF) therapies, which is a neat, holistic alternative that leverages your body’s own growth factors for rejuvenation.
You can definitely expect highly personalized treatments from their experienced team of professionals. However, a potential scheduling challenge might be the fact that they are closed on both Monday and Sunday.
This limits flexibility, especially if you require an appointment early in the week or during a full weekend day, which is a factor to consider when planning your visits.
Customer Reviews
I saw results in just two weeks!
Caroline is amazing!! She listened to me and actually saw me and saw right past my acne!! I’ve been to previous physicians for my acne issues and Caroline not only treated me but resolved my issues and I saw results in just two weeks. I highly recommend this med spa and Caroline. They are truly amazing!! I feel so much more confident in my skin!!
- alyssa dickinson | Google Review
Will most definitely be returning!
Dr Caroline is nothing short of amazing! I felt instantly at ease. She is so kind, smart, knowledgeable, and sincere. She talked through what I wanted and how we could achieve it. I received Botox and lip filler and will most definitely be returning! Thank you thank you Dr Caroline!
- Kelly Hidy | Google Review
5. Üesthetics

Website: https://uestheticsindy.com/
Address: 711 S East St Ste 1B
Contact: +1 317-377-4448
Hours: Tue – Fri: 10:00 AM – 5:00 PM
Üesthetics is ideal for clients seeking subtle, refreshed results rather than dramatic change.
Its philosophy of natural enhancement focuses on enhancing your natural beauty, not altering it, through conservative, personalized treatments that avoid an overdone look.
The highly credentialed team includes nurse practitioners, registered nurses, and licensed estheticians, ensuring safe, medically sound care.
A standout advantage is the use of the aerolase neo elite non-ablative laser, which is safe for all skin types and effectively treats concerns ranging from acne to melasma.
Education is central to the experience, empowering patients to make informed decisions about long-term skin health and aesthetics. This thoughtful, restrained approach appeals to those who value balance and authenticity in cosmetic care.
One consideration is that all services are appointment only, so visits require advance planning rather than walk-in convenience for busy modern clients today seeking flexibility.
Customer Reviews
Very professional and takes the time to listen to your needs
I’ve had the pleasure of dealing with Meghan a couple times for some touch up services. She is very professional and takes the time to listen to your needs. She was very knowledgeable with the procedures i was looking for and answered every question I had. I’d highly recommend U Esthetics. I will definitely be returning.
- Jesus Lopez | Google Review
They simply help you look and feel your best!
Jamie and everyone I’ve been to for tox treatments are fabulous and they treat you like a real human. They aren’t trying to over sell you, like some places. They simply help you look and feel your best!
- Annie Burns | Google Review




